Cofactor - definition of cofactor by The Free Dictionary https: One of two or more contributing factors. A substance, such as a metallic ion or coenzyme, that must be associated with an enzyme for the enzyme to function.
Mathematics maths a number associated with an element in a square matrix, equal to the determinant of the matrix formed by removing the row and column in which the element appears from the given determinant.
Biochemistry biochem a nonprotein substance that forms a complex with certain enzymes and is essential for their activity.
It may be a metal ion or a coenzyme. Switch to new thesaurus. References in periodicals archive?
Ryan points to the enzyme's use of an iron-based cofactor to sustain a reaction, similar to what was observed from anammox bacteria. Revealing the knotty roots of natural products.
Hydrogen borrowing requires mutually compatible cofactors shared by two enzymes and in some cases will require redesign of cofactor specificity. Biocatalytic Amine Synthesis via Hydrogen Borrowing.
From kinetic and spectroscopic analysis of FeMo cofactor Thomas Spatzal et al. DFT analysis of metal complexes for selective nitrogen removal from the syngas based on binding energy criteria.
Zinfandel is prone to boron deficiency, which is a cofactor of nitrate reductase. Considering mineral nutrient interactions: Biotin is a cofactor for acetyl-CoA carboxylase, a potentially rate-limiting enzyme in myelin synthesis. High-dose biotin for multiple sclerosis.
The reagents are fluorescent detection analytes that competitively bind to a key cofactor binding site of enzymes that catalyze methylation of histones, DNA, and RNA.
In this case, the initial VWD testing panel identified significantly decreased plasma von Willebrand factor ristocetin cofactor activity VWF: RCowith a discordantly low ratio of VWF: The amount of cofactor needed to achieve saturation is larger for an inefficient enzyme than for a normal enzyme.